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- W2381045437 abstract "Objective The application of endoscopic techniques in early judgment of the quality of nerve coaptation was introduced. The effect of endoscopic intervention on nerve regeneration was also evaluated. Methods 12 male adult Beagle dogs were divided into 3 groups, with 4 each. Sciatic nerves were transected 2cm proximal to the popliteal fossa and sutured immediately. Postoperative management varied according to group assignment. In group A (endoscopic group) the repaired sciatic nerve was endoscopically explored to examine the suture site and record nerve action potential and nerve conduction velocity two weeks after the operation. Neurolysis and electric stimulation was also delivered via endoscope. The procedure was repeated once every week until neonatal potential was detected at the distal part of the sciatic nerve. The same procedures were followed in group B (surgical group) except that all was done in open surgery. In group C (control) there was no postoperative intervention. Functional recovery and electrophysiological changes were followed, and the time when neonatal potential of triceps muscle appeared was recorded. Six months after the operation, the quality of nerve coaptation was judged by surgical exploration and electrophysiological detection. Results Regeneration potential was detected distal to the nerve coaptation site 3 weeks after the operation in groups A and B. In group C, regeneration potential was present 4 weeks postoperationly. Neonatal potential of the triceps muscle was recorded 6 weeks post-op in groups A and B and 7 weeks post-op in group C. Hindlimb function almost recovered in groups A and B 6 months after the operation. There were no significant differences in motor nerve conduction velocity and compound muscle action potential between these two groups. Compared with group C, both of them were statistically better (P0.05). Conclusion Endoscopic early detection of nerve suture quality and endoscopic intervention led to better nerve regeneration. The experimental results provided laboratory basis for potential clinical application." @default.
- W2381045437 created "2016-06-24" @default.
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- W2381045437 date "2005-01-01" @default.
- W2381045437 modified "2023-09-24" @default.
- W2381045437 title "Endoscopic intervention in management of peripheral nerve injuries: an experimental study" @default.
- W2381045437 hasPublicationYear "2005" @default.
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