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- W2381199652 abstract "Objective To explore the effects of erythromycin(EM)on the joint prosthesis polyethylene wear particles-induced bone resorption.Methods The osteoclasts of rabbits cocultured with bone slices and coverslips were divided into 6 groups of control(A),ultrahigh molecular weight polyethylene(UHMWPE)(B),and UHMWPE +EM 10(C),20(D),40(E),80μg/ml(F).After cultured for 48 hours,the quantity of osteoclasts and the areas of absorption lacunae were calculated.Results The areas of absorption lacunae were less in groups C,D,E and F than those in group B(P0.05).The area of absorption lacuna was in an order of group Dgroup Cgroup Fgroup E(P0.05).There was no statistical significance in the quantity of osteoclasts on coverslips among the 4groups.Conclusion EM can inhibit polyethylene wear particles-induced bone resorption." @default.
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- W2381199652 date "2008-01-01" @default.
- W2381199652 modified "2023-09-27" @default.
- W2381199652 title "Erythromycin inhibits polyethylene wear particles-induced bone resorption" @default.
- W2381199652 hasPublicationYear "2008" @default.
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