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- W2381268215 abstract "Object To explore the effect of interleukin-6(IL-6) and tumor necrosis factor alpha(TNF-α) on the pathogenesis of postmenopausal osteoporosis(PMOP).Methods According to the result of bone mineral density(BMD),76 postmenopausal women were allocated to three groups. 33 cases of PMOP were assigned to Group C,19 cases of postmenopausal women without osteoporosis to Group B,and 20 cases of healthy premenopausal women to group A. Serum levels of IL-6、TNF-α、estrogen(E2) and osteocalin (BGP)were detected by radioimmunoassay method. Results Serum levels of IL-6、TNF-α in Group C and Group B were higher than those in Group A,and higher in GroupC than in Group B; Serum level of BGP in Group C and Group B was higher than those in Group A,and higher in Group C than in Group B;the IL-6、TNF-αlevels were correlated negatively with BMD,positively with BGP.Conclusion The pathogenesis of PMOP is related to the high serum levels of IL-6 and TNF-α." @default.
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- W2381268215 date "2007-01-01" @default.
- W2381268215 modified "2023-09-27" @default.
- W2381268215 title "Effects of interleukin-6、tumor necrosis factor alpha on the pathogenesis of postmenopausal osteoporosis" @default.
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