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- W2381269096 abstract "Objective The aim of this study is to observe the high concentration of immunomodulatory drugs suppress the expression of IL-6 and IL-8 in S180 sarcoma mice.Methods S180 sarcoma mice were set up and then randomly divided into four groups:Control、Model、CTX and HIS.After 10 days of different treatments,the mice were killed and the weight of spleen and tumor,spleen indexinhibition rates of tumor in mice were measured.The level of IL-6 was measured by ELISA; The expression of IL-10 in tumor cell were investigated by Western blot.Results Comparedwith the model group,HIS can improve immunity by increasing the spleen index in S180sarcoma mice.In ELISA experiment,the level of IL-6 were downregulate.Western Blot showed HIS decrease the expression of IL-10.Conclusion HIS inhibites the growth of tumors,improves the immunity of mice via down-regulating the expression of IL-6 and IL-10." @default.
- W2381269096 created "2016-06-24" @default.
- W2381269096 creator A5056384088 @default.
- W2381269096 date "2013-01-01" @default.
- W2381269096 modified "2023-09-28" @default.
- W2381269096 title "Regulating Effect of High-efficiency Immune Modulators on Expression of Interleukin-6 and Interleukin-8 in S_(180) Sarcoma Mice" @default.
- W2381269096 hasPublicationYear "2013" @default.
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