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- W2381277985 abstract "Objective: To explore the effect of superoxide dismutase (SOD)on inhibition of HepG2 hepatocellular cancer cell proliferation. Methods:Using gene transfer technique, hepatocellular cancer cells(HepG2) were transfected with retroviral vector containing human CuZnSOD cDNA and the elevated SOD gene expression was compared with the parental and neo control cells. The biological characteristics of the cells were measured. Results:Compared with the control cells, cancer cells transfected with SOD gene showed an inhibited growth rate,an increased cell mass, a reduced number of cells in S phase and a decreased clone forming ability in soft agar as well as a smaller tumor size formed in nude mice. Conclusion: The CuZnSOD gene overexpression could inhibit the proliferation of HepG2 hepatocellular cancer cells." @default.
- W2381277985 created "2016-06-24" @default.
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- W2381277985 date "1998-01-01" @default.
- W2381277985 modified "2023-09-25" @default.
- W2381277985 title "THE EFFECT OF CuZnSOD GENE ON INHIBITION OF THE PROLIFERATIONOF HepG2 HEPATOCELLULAR CANCER CELLS" @default.
- W2381277985 hasPublicationYear "1998" @default.
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