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- W2381285514 abstract "Objective: To evaluate the efficacy and safety of Lipo-prostaglandin E1 combined with methylcobalamin on treating diabetic peripheral neuropathy.Methods: The electronic databases CNKI was searched to collect randomized controlled trials by interventions of Lipo-prostaglandin E1 combined with methylcobalamin for the treatment of diabetic peripheral neuropathy.The methodological quality of the trials were evaluated and the valid data for Meta-analysis were extracted.Results: 11 randomized controlled trials and 1013 patients were included.Test group was treated with Lipo-prostaglandin E1 and methylcobalamin,while control group was treated on the basis of combined therapy plus B vitamins.Meta analysis showed that the test group of patients with diabetic peripheral neuropathy was better than the control group in improving the clinical symptoms(P0.01).Conclusions: Lipo-prostaglandin E1 combined with methylcobalamin can improve the clinical symptoms in patients with DPN.However,due to the low quality of research literature,more scientific and standardized,high quality,large sample,long-term follow-up of the randomized controlled trials are still needed." @default.
- W2381285514 created "2016-06-24" @default.
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- W2381285514 date "2011-01-01" @default.
- W2381285514 modified "2023-09-25" @default.
- W2381285514 title "Effects of Lipo-Prostaglandin E1 Combined with Methylcobalamin on Diabetic Peripheral Neuropathy:A Meta-Analysis" @default.
- W2381285514 hasPublicationYear "2011" @default.
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