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- W2381393960 abstract "Objective:To explore the relationship between the expression of T-bet gene in peripheral blood mononuclear cells(PBMC)and pathogenesis of aplastic anemia(AA).Methods:T-bet mRNA expression in PBMC was semi-quantitatively analyzed by the reverse transcription PCR(RT-PCR)and the serum level of interferon-γ(IFN-γ)was detected by ELISA in total 37 cases,including 17 cases of the firstly diagnostic patients with AA,and 20 healthy individuals as controls.Results:As compared with those in normal control group,the expression of T-bet in PBMC and the serum level of IFN-γ in the firstly diagnostic patients with AA increased with significant difference(P0.01),the correlativity of them appeared positive(P0.05).Conclusions:The increased expression of both T-bet and IFN-γ may play an important role in immunopathology of AA." @default.
- W2381393960 created "2016-06-24" @default.
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- W2381393960 date "2009-01-01" @default.
- W2381393960 modified "2023-10-12" @default.
- W2381393960 title "Expression of T-bet in peripheral blood mononuclear cells of patients with aplastic anemia and its significance" @default.
- W2381393960 hasPublicationYear "2009" @default.
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