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- W2381410630 abstract "Objective To observe the gene expression of collagen BMP-2 (bone morphogenetic protein-2) and TGF-β (transforming growth factor-β) in human thoracic ligamentum flavum.Method BMP-2 and TGF-13 probes were labeled and in situ hybridization results were analyzed by VIDAS system.Result (1) Under 20 years group:the positive gene expression of TGF-β was evident,but it was negative to BMP-2.(2) 21 ~40 years group:there were a few positive signal of both BMP-2 and TGF-β on the insertion part.(3) 41 ~60 years group:there was only few TGF-β positive signal on insertion part,but BMP-2 gene expression was relatively high.(4) Over 61 years group:there was not TGF-β expression,but BMP-2 expression could only be seen on insertion part and junction part,and was low,but the cells were areatus.Conclusion In normal ligamentum,there is expression of TGF-β gene,but it decreases with age;with age advancing BMP-2 emerges and enhances in the insertion part of ligamentum flavum." @default.
- W2381410630 created "2016-06-24" @default.
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- W2381410630 date "2005-01-01" @default.
- W2381410630 modified "2023-09-23" @default.
- W2381410630 title "Gene expression of collagen BMP-2 and TGF-β in human lumbar ligamentum flavum" @default.
- W2381410630 hasPublicationYear "2005" @default.
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