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- W2381443432 abstract "Objective:To observe the effect and mechanism of electroacupuncture atBL 32on detrusor hyperreflexia.Methods:Forty-four adult female Sprague-Dawley rats were selected,but only thirty-seven were included into the trial after spinal cord injury(SCI),from which sixteen were randomized into treatment group,sixteen into control group and five into normal group(sham surgery group).Electro-acupuncture(20Hz,continuous wave)at bilateralBL 32were given to treatment group after incontinence occurred for 2 hours for 14 times.The other two groups were not given any treatment.All groups were accepted urodynamics detection before the first and after the last treatment,and accepted immunohistochemical staining to observe the VR1 impression after the last treatment.Results:The maximum bladder pressure(MBP)increased in rats with DH(electro-acupuncture group and model group)(P0.05),the maximum bladder compliance(MBC)decreased(P0.05)and the VR1 expression increased in the sacral micturition center after SCI(P0.05).After treatment,the MBP of electro-acupuncture group significantly decreased(P0.05),having no difference with normal group(P0.05);the MBP of model group significantly decreased(P0.05),but having significant difference with normal group(P0.05).The MBC in electro-acupuncture group increased significantly(P0.05),but no change in model group(P0.05).The VR1 expression in sacral micturition center was less in the electro-acupuncture group than in the model group but more than the normal group(P0.05).Conclusion:Electro-acupuncture at BL 32 can inhabit the over-activity of bladder in SCI rats and reduce the VR1 expression in the sacral micturition,which showed that the C-fiber's activity was weakened,which maybe one of the mechanisms of EA at BL 32 in treating DH." @default.
- W2381443432 created "2016-06-24" @default.
- W2381443432 creator A5090492172 @default.
- W2381443432 date "2010-01-01" @default.
- W2381443432 modified "2023-09-26" @default.
- W2381443432 title "Effect of Electroacupuncture at BL 32 on VR1 Expression in the Sacral Micturition Center of Rats with Detrusor Hyperreflexia" @default.
- W2381443432 hasPublicationYear "2010" @default.
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