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- W2381475017 abstract "OBJECTIVE To establish HPLC methods for the determination of trifiuoperazine hydrochloride and its related substances.Methods C18 column was used,the mobile phase wasacetonitrile-phosphate buffered solution(0.05 mol·L-1 NaH2PO4·2H2O 100mL,add 2 mLtriethylamine,and adjusted to pH 3.0 with phosphoric acid)(38∶62).The flow rate was 1.0ml·min-1,the column temperature was 30℃ and the detection wavelength of UV detector was258 nm.RESULTS trifluoperazine hydrochloride was separated completely from impurities.Thelinear range of trifluoperazine hydrochloride was 2.5～25μg·mL-1(r=0.9997).The limit of quantitation was 0.016ug·mL-1.CONCLUSION With good sensitivity,accuracy,and selectivity,the method can be applicable for the determination of trifiuoperazine hydrochloride and its related substances." @default.
- W2381475017 created "2016-06-24" @default.
- W2381475017 creator A5078314620 @default.
- W2381475017 date "2010-01-01" @default.
- W2381475017 modified "2023-09-26" @default.
- W2381475017 title "Determination of trifluoperazine hydrochloride and its related substances by HPLC" @default.
- W2381475017 hasPublicationYear "2010" @default.
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