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- W2381487890 abstract "Objective It is to investigate the effect of high dosage of vitamin D3 on Cardiovascular and renal pathological change in rats.Methods SD rats were randomly divided into 2 groups,group A were given normal saline and group B given vitamin D3 400 000 IU/(kg·d) by intragastric administration once per day and for 3 days.Both groups were given Calcein with hypodermic injection at dose of 7 mg/kg on seventh day.On eighth day,heart,aortic arch,kidney of the rats were get to be stained with HE method to observe the pathological changes.Renal calcification was also observed by fluorescence microscope.Results The pathological observation showed that cardiovascular system and kidney were both suffered from multiple calcifications.Conclusion Hypervitaminosis of vitamin D3 can cause cardiovascular and renal multiple calcification in rats." @default.
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- W2381487890 date "2007-01-01" @default.
- W2381487890 modified "2023-09-23" @default.
- W2381487890 title "Effect of high dosage of vitamin D3 on Cardiovascular and renal pathological change in rats" @default.
- W2381487890 hasPublicationYear "2007" @default.
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