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- W2381532495 abstract "A rapid and simple quantitative analytical method for deter-mination of plasma prazosin was developed. Saturated sodium chloridesolution, sodium hydroxide solution and ether were added into the plasmasample. Under alkaline condition, saltout effect increases the extractionrate of prazosin by ether. Further, the prazosin was extracted into sulfuricacid from the ether layer. The extract was examined in a spectrophoto-fluorimeter with excitation at 248 nm and measurement at 388 nm. Theextraction rate of prazosin from plasma was 71%. The sensitivity limit is1 ng/ml in plasma. The accurracies of this method were 95. 2±8.53%,102. 7 ±4. 1840 and 101. 5 ±1. 68% at the concentration of 2, 10 and 50ng/ml,respectively. A satisfactory result has been achieved in clinical pharma-cological investigation using this method." @default.
- W2381532495 created "2016-06-24" @default.
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- W2381532495 date "1991-01-01" @default.
- W2381532495 modified "2023-09-24" @default.
- W2381532495 title "A RAPID SIMPLE SPECTROPHOTOFLUORIMETRY FOR DETERMINATION OF PLASMA PRAZOSIN" @default.
- W2381532495 hasPublicationYear "1991" @default.
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