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- W2381584142 abstract "Objective:To evaluate the effect of insulin treatment for pregnancy outcome in patients with GIGT. Methods:108 patients with GIGT screened out from 716 pregnancy women by OGTT were divided into GIGT insulin treatment group(GIGT IT) and GIGT control group(GIGT C) randomly. Each group contained 54 patients. GIGT IT group were treated with insulin subcutaneous injection on the basis of dietary treatment,GIGT C group were only treated with diet. The outcome of pregnancy were then investigated. Results:① The morbidity of hypertensive state of pregnancy,polyhydramnios,premature rupture of membrane,cesarean section,fetal macrosomia,and fetal death were 3.70%, 5.56%,3.70%, 5.56%,0.oo% respectively in GIGT IT group; and 14.81%,24.07%,12.96 %,31.48%,37.04%,5.56% respectively in GIGT C group. There existed significant difference in morbidities of the complications of mother and neonate between two groups ( P 0.05,or P 0.01);②When FPG was 3.33～4.44 mmol/L,PG2h4.44～5.56 mmol/L,HbA c 4～6%,the morbidities of various complications of mother and neonate were the lowest, and hypoglucemia hardly occured in the gestational women; ③There was postive PG2h and HbAc birth weight correlations shown by this study. between PG2h 、 HbA c and birth weight of newborns ( r =0 5125,0.5679, respectively, both P 0.001). Conclusions:GIGT may increase the morbidities of the complications of mother and neonate during pregnancy. These morbidities of complications could be reduced significantly with insulin subcutaneous injection,the optimal plasma glucose levels during pregnancy may be FPG 3.33～4.44 mmol/L,PG2h4.44～5.56 mmol/L,HbA C 4～6%." @default.
- W2381584142 created "2016-06-24" @default.
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- W2381584142 date "2002-01-01" @default.
- W2381584142 modified "2023-09-25" @default.
- W2381584142 title "A Clinical Survey of Insulin Treatment in Patients with Gestational Impaired Glucose Tolerance(GIGT)" @default.
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