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- W2381633861 abstract "OBJECTIVE To study the change regulation of quantity-time(Q-t) in the uptake process of cucurbitacin B(CuB)by human hepatocellular carcinoma cells(HCC) in vitro.METHODS The experiment of HepG-2 cell uptaking CuB was used to study together with MTT assay,cell culture and HPLC-DAD technology.Finally Q-t relation of CuB was analyzed.RESULTS 10 μg·mL-1 and 4 h was the dosage and uptake time in the study.The uptake of CuB by HepG-2 cell was mild before 0.5 h,nearly lineally with 0.5-1 h,and peak at 2 h,the ratio was 30.37%.After 2 h,the uptake decreased unsignificantly.CONCLUSION The HCC line uptake of CuB has certain correlation to the dosage and uptake time.The method is successfully used in present study of HCC line uptake of CuB and it could also be applied in the other uptake study by cells." @default.
- W2381633861 created "2016-06-24" @default.
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- W2381633861 date "2012-01-01" @default.
- W2381633861 modified "2023-09-26" @default.
- W2381633861 title "Uptake process of cucurbitacin B by human hepatocellular carcinoma cells in vitro" @default.
- W2381633861 hasPublicationYear "2012" @default.
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