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- W2381640910 abstract "Objective To evaluate the changes of serum lipids、 nitric oxide(NO) and endothelin(ET) after treatment with wild grape root and Kiwi root in rats fed with hypercholesterol emulsion.Methods 55 male Wistar rats were randomly divided into control group(n = 11,normal diet),hyperlipidemia group(n=11,high-cholesterol emulsion) and Chinese medicine group(every group n = 11,high-cholesterol emulsion plus corresponding Chinese medicine :(8g/kg/d,11g/kg/d,).Western medicine group(n = 8,high-cholesterol emulsion plus simvastatin).During 6 weeks of the experiment,serum lipids were compared among the 5 groups.,the levels of NO and ET in serum were also measured.Results After 6 weeks of treatment with Ye Putao root and Kiwi root,the levels of serum lipids were all decreased as compared with hyperlipidemia group(all P0.05);the NO level in serum was increased significantly,while the ET level was markedly decreased as compared with hyperlipidemia group(P 0.05,0.01).Conclusion Wild grape root、Kiwi root could effectively decrease the level of serum lipids,increase NO and decrease ET.The changes of NO and ET may play a role in the progress of hyperlipidemia.It confirmed that wild grape root and Kiwi root have certain effect on the hyperlipidemia and hypertension." @default.
- W2381640910 created "2016-06-24" @default.
- W2381640910 creator A5003428837 @default.
- W2381640910 date "2010-01-01" @default.
- W2381640910 modified "2023-09-23" @default.
- W2381640910 title "Experimental Study on the Effect of Wild Grape Root、Kiwi Root on Nitric Oxide and Endothelin in Hyperlipidemia Rats" @default.
- W2381640910 hasPublicationYear "2010" @default.
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