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- W2381706355 abstract "Objective:To study the IgG antibody level of BALB/c mice immunized by HPV 16 L1 E7 recombinant adenovirus type 5 (rAd 5HPV 16 L1 E7) virus and plasmid through different immunopaths.Methods:rAd 5HPV 16 L1 E7 virus was propagated in the 293 cell line and plasmid prepared.The BALB/c mice were immunized with these two types vaccines through different paths:intramuscular injection,intraperitoneal injection,nasal drip and stomach feeding.The serum IgG level of the mice was tested.Result:The levels of serum IgG antibody in the immunized BALB/c mice through different types of vaccines and different immunopaths were higher than those in the control BALB/c mice (P0.05),with the level of serum IgG in the mice immunized through intramuscular injection being the highest.Conclusion:Both rAd 5HPV 16 L1 E7 virus and plasmid can stimulate the mice producing humoral immunoresponse.The levels of serum IgG antibody is affected by the different vaccines and different immunopaths." @default.
- W2381706355 created "2016-06-24" @default.
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- W2381706355 date "2003-01-01" @default.
- W2381706355 modified "2023-09-25" @default.
- W2381706355 title "Study on serum IgG level of mice immunized with rAd_5HPV_(16)L1-E7 virus and plasmid" @default.
- W2381706355 hasPublicationYear "2003" @default.
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