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- W2381716072 abstract "Objective To investigate the role of Helicobacter pylori (Hp) infection in patients with idiopathic thrombocytopenic purpura (ITP),and to explore the therapeutic effect of Hp eradication.Methods ELISA for Hp urease B (ureB) was performed in 45 patients with ITP as well as in 32 normal individuals as that in the controls.Hp-positive ITP patients were treated with Hp eradication procedure,and their platelet counts were compared with those in the Hp-negative patients after treatment.Results The Hp-positive infection rates in the ITP group and control group were 66.7% and 43.8%,respectively (P 0.05).In 25 patients who received Hp eradication treatment,21 became Hp-negative,and their platelet counts were significantly increased in comparison with those in the Hp-negative ITP patients.Conclusion The frequency of Hp infection in ITP patients is higher than that in normal individuals.Part of chronic ITP patients whose Hp infection is successfully eradicated shows increase in platelet counts.These results suggest that Hp infection play an important role in ITP pathogenesis." @default.
- W2381716072 created "2016-06-24" @default.
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- W2381716072 date "2010-01-01" @default.
- W2381716072 modified "2023-09-27" @default.
- W2381716072 title "Measurement of Helicobacter pylori Urease B in Patients with ITP and Effect of Helicobacter pylori Eradication" @default.
- W2381716072 hasPublicationYear "2010" @default.
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