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- W2381746521 abstract "Objective:To explore the mechanism of electroacupuncture (EA) on thymocyte apoptosis in morphine withdrawal rats. Methods:Forty SD rats were randomly divided into the normal group,the control group,the dependence group and the electroacupuncture group (EA group). Rat abstinence syndrome model was established by continuous muscular injection of morphine to the hind limds for 20 days. EA therapy was given to rats in the EA group,EA was applied to Zusanli (ST36) for 30 min,once every day,for 7 successive days. Laser scanning confocal microtechnic was applied to observe the content of thymus intracellula Ca2+ in every group rats. Immunohistochemical method was applied to observe expression of PKA in every group rats. Results:Compared with normal,the content of thymus intra-cellula Ca2+ and expression of PKA in the control group and dependence group taked on increased tendency obviously. The content of thymus intra-cellula Ca2+ and expression of PKA taked on reduced tendency obviously after EA therapy. Conclusion:EA possesses the effect of regulating the content of thymus intra-cellula Ca2+ and expression of PKA,which might be one of the mechanisms of EA resisting thymus apoptosis in the morphine withdrawal rats." @default.
- W2381746521 created "2016-06-24" @default.
- W2381746521 creator A5042553551 @default.
- W2381746521 date "2010-01-01" @default.
- W2381746521 modified "2023-09-28" @default.
- W2381746521 title "Effect of Electroacupuncture on Expression of Pka and Content of [Ca~(2+)]i in Morphine Withdrawal Rats' Thymocyte" @default.
- W2381746521 hasPublicationYear "2010" @default.
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