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- W2381761346 abstract "Objective:To develop a HPLC method for simultaneous determination of metabolites of heroin,methamphetamine,MDA,MDMA and ketamine,understand the type of abused drugs and provide evidence for judiciary identification.Methods:Following solid-phase extraction with Strata-X C18 column,chromatography was performed on a Phenomenex Luna C18(250 mm×4.6 mm,5 μm)column,using acetonitrile-30 mmol·L-1NH4AC(10:90,v/v) as mobile PhaseⅠ,acetonitrile-30 mmol·L-1NH4AC(55:45,v/v)as mobile PhaseⅡ at a flow rate of 1.0 ml·min-1 and the wavelength was set at 210 nm.Results:The assay exhibited a good linear relationship with the limits of detection(S/N=3)ranging from 1.2 to 6.0 ng and the recoveries were 98.1%-101.0%.Conclusion:The established method is simple,selective and sensitive,which suggests that it be applied for drug analysis and surveillance on drug abuse." @default.
- W2381761346 created "2016-06-24" @default.
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- W2381761346 date "2008-01-01" @default.
- W2381761346 modified "2023-09-23" @default.
- W2381761346 title "SIMULTANEOUS DETERMINATION OF COMMON ABUSED DRUGS AND THE METABOLITES BY HPLC" @default.
- W2381761346 hasPublicationYear "2008" @default.
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