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- W2381823118 abstract "Background : It is not clear how much amount is favourable to coronary heart disease, although cardioprotective effects of red wine were reported. Furthermore, there is no report showing the effects of soju, the popular liqour in Korea on endothelial function. We performed this study to know early effects of alcohol on endothelial function in healthy subjects according to the kinds and the amounts of alcohol. Methods : Endothelial function was measured by using high-resolution ultrasound i n20healthy subjects. Ten subjects were crossover studied according to the types of alc ohol (120 cc of red wineand45ccofsoju)andtheothertensubjectswerestudiedusingthehalfdosage of the same alcohol. Results: The endothelial function can be impaired during 1 to 2 hours after alcohol ingestion (Soju45ccandredwine120cc, p<0.05), then recovered to baseline level. However, these impaired endothelial functions were associated with an increased brachial artery diameter. The endothelial function was recovered to baseline level more earlier in case of red wine tha n that of soju 2 hours vs 3 hours. Red wine 60cc and Soju 22.5 cc can improve the endothelial functio n in healthy subjects 2 and 3 hours after ingestion, respectively. These effects were not related with vasodilatory effects of alcohol. Conclusion : This study suggests that small amounts of alcohol can improve the endothel ial function in healthy subjects independently with the vasodilatory effectsof alcohol.The amounts of alcohol showing beneficial effects on endothelial function were lower thanourexpectation(ahalf cup).(Korean J Med 69:284-292, 2005)" @default.
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- W2381823118 date "2005-01-01" @default.
- W2381823118 modified "2023-10-18" @default.
- W2381823118 title "Early effect of alcohol on endothelial function according to the kinds and the amounts of alcohol in healthy subjects" @default.
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