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- W2381874254 abstract "Objective; To investigate the changes of nitric oxide synthase (NOS) activities in brain cortex and brain stem of rats along with the increase of rat age. Methods: Experimental rats were divided into 3 groups: developing period (3 months of age, DVP) , autumn period (12 months of age, ATP) , and aging period (18 months of age, AGP). The neuronal NOS activities in the brain cortex and brain stem of them were determined with reagent kit. Results: In AGP group, the NOS activity was 44. 96 ±7. 11 nmol/min · g-1 in brain cortex, and was higher than those of DVP and ATP groups (38. 56 ± 7. 23 nmol/min · g-1, and 39. 53 ± 8. 26 nmol/min · g-1, P 0. 01). There was no difference between NOS activities in brain cortex of DVP and ATP groups (P 0. 05 ) . The NOS activities in brain stem of AGP group was 45. 84 ±7. 53 nmol/min· g-1, and it was significantly higher than those of DVP and ATP groups (32. 13 ±6. 26, and 38. 68 ±7. 81 nmol/min · g-1, P 0. 01). There was significant difference between the latter 2 data ( P 0. 05 ). Conclusions: The NOS activities in rat brain are increasing with aging, but there are distinguishing differences in regions." @default.
- W2381874254 created "2016-06-24" @default.
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- W2381874254 date "2003-01-01" @default.
- W2381874254 modified "2023-09-24" @default.
- W2381874254 title "A Comparative Study on the Activity of NOS in Cerebral Cortex and Brain Stem of Rats at 3 Different Developing Stages" @default.
- W2381874254 hasPublicationYear "2003" @default.
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