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- W2381926962 abstract "Objective:To investigate the protective effects of glycine in cardiomyocyte subjected on ischemia and hypoxia. Methods:Cardiomyocytes model were established in vitro.The content of ATP,ADP and AMP were tested by high performance liquid chromatogram(HPLC).Results:The content of ATP of cardiomyocytes subjected to ischemia and hypoxia were significantly lower (P0.01)after 1 h.On the contrary,the content of ADP and AMP were significantly higher.The change of ATP/ADP was similar with ATP.However,when cardiomyocytes were subjected to glycine(5 mmol/L)combined with ischemia and hypoxia,the content of ATP and ATP/ADP were increased and the content of ADP and AMP were significantly decreased than those without treatment of glycine (P0.01).Conclusion:Glycine can improve obviously the energy metabolism of cardiomyocytes subjected to ischemia and bring into protection effect." @default.
- W2381926962 created "2016-06-24" @default.
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- W2381926962 date "2008-01-01" @default.
- W2381926962 modified "2023-09-24" @default.
- W2381926962 title "Protective effects of Glycine in cardiomyocyte subjected to ischemia and hypoxia" @default.
- W2381926962 hasPublicationYear "2008" @default.
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