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- W2381953867 abstract "Objective To study the clinical significance of detecting serum levels of IL-17,ECP and IgE in children with bronchial asthma(BA). Method The serum levels of IL-17,ECP and IgE were detected in 82 children with lightmidrange asthma and compared with those of 20 healthy children in the healthy control group. Results The serum levels of IL-17,ECP and IgE in the BA group were significantly higher than those in the healthy control group,there were significant differences(all P0.01).The serum levels of ECP and IgE in the acute exacerbation group were significantly higher than those in the remission group(all P0.01),and the serum level of IL-17 in the acute exacerbation group was mildly higher than that in the remission group,but there were no significant differences(P0.05).The serum level of ECP was actively correlated with the serum levels of IgE in children with asthma(r=0.337,P0.01).The serum level of IL-17was no actively correlated with the serum level of ECP and IgE.But the serum levels of IL-17was actively correlated with the serum level of ECP and IgE in the acute exacerbation group(r=0.314 and 0.325,P0.05). Conclusions IL-17,as a complicated cytokine,is possibly involved in eosinophilic inflammation mediating asthma.Detecting the change of the serum level of ECP and IgE is of very important clinical value in detection and treatment of pathogenetic inflammation for children with bronchial asthma." @default.
- W2381953867 created "2016-06-24" @default.
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- W2381953867 date "2013-01-01" @default.
- W2381953867 modified "2023-09-23" @default.
- W2381953867 title "Clinical significance of serum levels of IL-17,ECP,and IgE detection in children with bronchial asthma" @default.
- W2381953867 hasPublicationYear "2013" @default.
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