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- W2381979084 abstract "The ORF3 genes of 29 PRRSV,isolated from Changjiang river basin in China from 2006,were amplified,cloned and sequenced with RT-PCR for analyzing the genetic variation of PRRSV,and blast with the representative isolates.The results showed that ORF3 of all isolates encode the minor structural proteins GP3,254 amino acids.All 29 PRRSV isolates belonged to the North American genotype,while 84.6%-100% amino acid identity with each other.It shared 85.0%-97.2% sequence identity with VR-2332,the representative North American strains of PRRSV.And it shared 86.6%-100% sequence identity with the highly pathogenic PRRSV.The phylogenetic trees indicated that the 29 PRRSV were further divided into two subgenotypes,28 isolates posses a same branch with the highly pathogenic PRRSV,and HZ24 shares a more closely relationship with RespPRRS vaccine.Meanwhile,there are mutation in the epitopes and the antigenic index of GP3 in all 29 isolates." @default.
- W2381979084 created "2016-06-24" @default.
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- W2381979084 date "2011-01-01" @default.
- W2381979084 modified "2023-09-28" @default.
- W2381979084 title "Genetic Variations of ORF3 Gene of PRRSV Isolates from Changjiang River Basin in China" @default.
- W2381979084 hasPublicationYear "2011" @default.
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