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- W2382040286 abstract "Objective:To observe the therapeutic effect of Chushi Huayu Pre- scription (CLIP) on early renal impairment in gout patients.Methods:A small- sample self-control open trial was carried out in 22 gout patients without obvious damage of glomerular filtrating function after an intermission over one month.The gout patients were given CHP (mainly composed of Rhizomu Smilacis Glabrae,Rhizoma Dioscoreue Hypoglaueae,Semen Coieis,Herba Lysimachiae,Herba Plataginis, Radix Selviae Miltiorrhizae,Radix Astragali,Radix et Rhizoma Rhei,Radix Gly- cyrrhizac) for one continuously month.The changes of blood uric acid (BUA),blood urea nitrogen (BUN) and creatinine (Cr) as well as the parameters of early renal tubular injury such as urinary N-acetyl-β-D-glucosaminidase(NAG) and lysozyme (LYZ) were observed before and after treatment.The levels of urinary NAG and LYZ in 15 healthy volunteers served for the normal reference.Results:The uri- nary levels of NAG and LYZ in the gout patients before treatment were higher than those in the normal control.The levels of BUA,BUN and Cr after treatment did not differ from those before treutment but the urinary levels of NAG and LYZ differed from those before treatment (P0.05).Conclusion:CHP has no effect on the high blood uric acid level in gout patients but has protective effect on renal tubular injury induced by high blood uric acid level." @default.
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- W2382040286 date "2008-01-01" @default.
- W2382040286 modified "2023-09-28" @default.
- W2382040286 title "Therapeutic Effect of Chushi Huayu Prescription on Renal Function of Gout Patients" @default.
- W2382040286 hasPublicationYear "2008" @default.
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