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- W2382058051 abstract "Objective To evaluate the clinical value of bone marrow mesenehymal stem cell trans- plantation on acute myocardial infarction in pig with myocardial perfusion imaging.Methods Acute myo- cardial infarction models were established by 21 minitype Chinese pigs and were divided into two groups. After 10 days,experimental group(n=11)was transplanted with bone marrow mesenchymal stem cell at the infarct areas,and the control group(n=10)with incubation solution.Before and eight weeks after transplan- tation,both groups were examined by ~(99)Tc~m-methoxyisobutylisonitrile(MIBI)myocardial perfusion imaging and with semi-quantitative analysis.Besides.echocardiogram and immunohistochemistry were also performed. Results There was significant difference of total myocardial perfusion abnormal segments(46 vs 26),infarct areas[(34±12)% vs (21±10)%]and myocardial ischemia score[(20.0±4.3)vs(12.1±3.6)]be- tween two groups(P0.05).Also,there were accordant results with echocardiogram and immunohisto- chemistry findings.Conclusions Bone marrow mesenchymal stem cell transplantation may improve blood perfusion and viability of the ischemic areas.Myocardial perfusion imaging can accurately observe the sur- vival of bone marrow mesenchymal stem cell transplanted at the infarct areas." @default.
- W2382058051 created "2016-06-24" @default.
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- W2382058051 date "2006-01-01" @default.
- W2382058051 modified "2023-09-28" @default.
- W2382058051 title "The myocardial perfusion imaging of bone marrow mesenchymal stem cell transplantation treated acute myocardial infarction in pig" @default.
- W2382058051 hasPublicationYear "2006" @default.
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