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- W2382078166 abstract "Sodium alginate, a kind of marine polysaccharide widely spread, has extensive biological activities. In this paper, alginate oligosaccharides were obtained by acid hydrolysis of sodium alginate. An oxidative damage model for the microglial cell was established combined the pre-protection by alginate oligosaccharides and treatment of H2O2 after determination of anti-oxidant capacity in vitro by alginate oligosaccharides, and a series of assays were performed including cell morphology and viability, scavenging capacity of ROS in vivo, the activities of key redox enzymes, thus proving the protection effect for the cell by alginate oligosaccharides, which efficiently scavenged ROS and sustained normal cell morphology, improving enzymatic activities for SOD and GSH-Px, finally relieving the cellular oxidative damage caused by H2O2. The research above could provide some clues for further exploration of mechanism in neurodegenerative diseases caused by activation of microglial cells." @default.
- W2382078166 created "2016-06-24" @default.
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- W2382078166 date "2015-01-01" @default.
- W2382078166 modified "2023-09-27" @default.
- W2382078166 title "Study on the Anti-oxidant Activity of Alginate Oligosaccharides" @default.
- W2382078166 hasPublicationYear "2015" @default.
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