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- W2382099856 abstract "V proteins are non-structural proteins of paramyxovirus that are generated due to the use of different open reading frame within P gene and are responsible for interferon(IFN)resistance.V protein is produced in a varity of forms in different paramyxovirus families.The IFN resistance effect of the V proteins have been extensively investigated by using reverse genetics systems,RNA interfere methods and detecting the crucial proteins related to IFN synthesis and signal pathway of IFN inhibition.These study have revealed that V proteins can directly block the induction of IFN,the activation of IFN signaling pathways or both of them.The present paper reviewed recent researches on paramyxovirus V proteins,IFN synthesis,antiviral mechanism of IFN and,especially,IFN resistance effect of V proteins.The further application of V proteins was also prospected." @default.
- W2382099856 created "2016-06-24" @default.
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- W2382099856 date "2008-01-01" @default.
- W2382099856 modified "2023-09-25" @default.
- W2382099856 title "Advance in Paramyxovirus V Proteins and Their Interferon Resistance Effects" @default.
- W2382099856 hasPublicationYear "2008" @default.
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