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- W2382102997 abstract "OBJECTIVE:To establish an RP-HPLC method for determination of clopidogrel and aspirin in human blood serum. METHODS:The separation was performed on Hypersil ODS C18 column. The mobile phase was 0.01 mol·L-1 potassium dihydrogen phosphate-methanol (35 ∶ 65)(adjust pH to 3 by phosphoric acid),with column temperature set at 30 ℃. The flow rate was 1.0 mL·min-1 and detection wavelength was 235 nm. RESULTS:The calibration curves were linear over the range of 0.25~16.0 mg·L-1(r=0.999 9)for clopidogrel and 0.125~8.0 mg·L-1(r=0.999 6)for aspirin. The average recoveries were 98.3% and 99.6%,respectively. RSD of intra-day and inter-day validatin were all below 10%. CONCLUSION:The method is convenient,rapid,and sensitive for determination and analysis of clopidogrel and aspirin in human serum." @default.
- W2382102997 created "2016-06-24" @default.
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- W2382102997 date "2010-01-01" @default.
- W2382102997 modified "2023-09-28" @default.
- W2382102997 title "Determination of Clopidogrel and Aspirin in Human Blood Serum by RP-HPLC" @default.
- W2382102997 hasPublicationYear "2010" @default.
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