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- W2382152148 abstract "Objective:To observe schizophrenia patients' liver injury caused by antipsychotic drugs and the feasibility of using Diammonium Glycyrrihizinate to prophylaxis and cure liver function injury.Methods:967 cases of schizophrenic patients from January 2001 to December 2011 in our hospital were retrospectively analyzed,using t test 、χ2 test、logistic regression analysis to observe the rate of liver function injury caused by antipsychotic drugs and the curative effect of Diammonium Glycyrrihizinate.Results: The incidence of liver function injury was 15.62%,it's associated with the continuous time that drugs taken;most of them took place in 4-6 weeks after drugs taken.Obviously,the rate of liver function injury caused by dispersal was much lower than chlorpromazine.The incidence of liver function injury was remarkably reduced by using Diammonium Glycyrrihizinate meanwhile.when patients find liver function injury,taking Diammonium Glycyrrihizinate orally,the liver function can become normal gradually,the effect was remarkable.Conclusions: The incidence of liver function that induced by atypical antipsychotic drugs was less than induced by classical drugs.The curative effect of Diammonium Glycyrrihizinate to prophylaxis and treat liver function injury caused by antipsychotic drugs was conclusive." @default.
- W2382152148 created "2016-06-24" @default.
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- W2382152148 date "2012-01-01" @default.
- W2382152148 modified "2023-09-26" @default.
- W2382152148 title "The clinical observation of schizophrenia patients' liver function injury caused by antipsychotic drugs" @default.
- W2382152148 hasPublicationYear "2012" @default.
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