Matches in SemOpenAlex for { <https://semopenalex.org/work/W2382173714> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2382173714 abstract "AIM: To observe the synergetic analgesic effects of low dose of haloperidol, a dopamine antagonist and under-threshold dose of morphine on mice induced by thermal and acetic acid, and to analyze the major mechanism of their synergetic actions. METHODS: To examine the analgesic synergetic effect of haloperidol (0.315 mg/kg, 0.625 mg/kg, 1.25 mg/kg, ip respectively), morphine (3.125 mg/kg, 6.25 mg/kg, 12.5 mg/kg ip, respectively) or combining effect of haloperidol (0.3125 mg/kg) with morphine (3.125 mg/kg) on mice, we compared the change of pain threshold stimulated by thermal, latent period of twisting, the number of times of twisting by acetic acid, and we also estimated the antagonistic effect of d -amphetamine (10 mg/kg) and naloxone (5 mg/kg) on haloperidol and morphine group. RESULTS: Combination of haloperidol with morphine significantly enhanced pain threshold of mice induced by thermal, prolonged latent period of twisting and decreased the number of times of twisting. Naloxone markedly antagonized the combination of analgesic action of haloperidol and morphine and not d -amphetamine. CONCLUSION: Combination of haloperidol with morphine have synergetic analgesic effect and morphine is the dominant factor." @default.
- W2382173714 created "2016-06-24" @default.
- W2382173714 creator A5034668164 @default.
- W2382173714 date "2002-01-01" @default.
- W2382173714 modified "2023-09-25" @default.
- W2382173714 title "A dopamine receptor antagonist modulates or enhances the analgesia of morphine and analysis of their synergetic analgesic mechanism" @default.
- W2382173714 hasPublicationYear "2002" @default.
- W2382173714 type Work @default.
- W2382173714 sameAs 2382173714 @default.
- W2382173714 citedByCount "0" @default.
- W2382173714 crossrefType "journal-article" @default.
- W2382173714 hasAuthorship W2382173714A5034668164 @default.
- W2382173714 hasConcept C120069818 @default.
- W2382173714 hasConcept C134018914 @default.
- W2382173714 hasConcept C170493617 @default.
- W2382173714 hasConcept C185592680 @default.
- W2382173714 hasConcept C2776885963 @default.
- W2382173714 hasConcept C2777389121 @default.
- W2382173714 hasConcept C2778750930 @default.
- W2382173714 hasConcept C2780820201 @default.
- W2382173714 hasConcept C2780948584 @default.
- W2382173714 hasConcept C2781353949 @default.
- W2382173714 hasConcept C513476851 @default.
- W2382173714 hasConcept C55493867 @default.
- W2382173714 hasConcept C71924100 @default.
- W2382173714 hasConcept C98274493 @default.
- W2382173714 hasConceptScore W2382173714C120069818 @default.
- W2382173714 hasConceptScore W2382173714C134018914 @default.
- W2382173714 hasConceptScore W2382173714C170493617 @default.
- W2382173714 hasConceptScore W2382173714C185592680 @default.
- W2382173714 hasConceptScore W2382173714C2776885963 @default.
- W2382173714 hasConceptScore W2382173714C2777389121 @default.
- W2382173714 hasConceptScore W2382173714C2778750930 @default.
- W2382173714 hasConceptScore W2382173714C2780820201 @default.
- W2382173714 hasConceptScore W2382173714C2780948584 @default.
- W2382173714 hasConceptScore W2382173714C2781353949 @default.
- W2382173714 hasConceptScore W2382173714C513476851 @default.
- W2382173714 hasConceptScore W2382173714C55493867 @default.
- W2382173714 hasConceptScore W2382173714C71924100 @default.
- W2382173714 hasConceptScore W2382173714C98274493 @default.
- W2382173714 hasLocation W23821737141 @default.
- W2382173714 hasOpenAccess W2382173714 @default.
- W2382173714 hasPrimaryLocation W23821737141 @default.
- W2382173714 hasRelatedWork W1974642290 @default.
- W2382173714 hasRelatedWork W1980393491 @default.
- W2382173714 hasRelatedWork W1983177446 @default.
- W2382173714 hasRelatedWork W1989755623 @default.
- W2382173714 hasRelatedWork W1996005744 @default.
- W2382173714 hasRelatedWork W2034642111 @default.
- W2382173714 hasRelatedWork W2068333023 @default.
- W2382173714 hasRelatedWork W2084647638 @default.
- W2382173714 hasRelatedWork W2097635080 @default.
- W2382173714 hasRelatedWork W2116906589 @default.
- W2382173714 hasRelatedWork W2128930785 @default.
- W2382173714 hasRelatedWork W2184764309 @default.
- W2382173714 hasRelatedWork W2257513838 @default.
- W2382173714 hasRelatedWork W2342995028 @default.
- W2382173714 hasRelatedWork W2425512505 @default.
- W2382173714 hasRelatedWork W2460666810 @default.
- W2382173714 hasRelatedWork W2800998171 @default.
- W2382173714 hasRelatedWork W3115291018 @default.
- W2382173714 hasRelatedWork W2074499962 @default.
- W2382173714 hasRelatedWork W2402177125 @default.
- W2382173714 isParatext "false" @default.
- W2382173714 isRetracted "false" @default.
- W2382173714 magId "2382173714" @default.
- W2382173714 workType "article" @default.