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- W2382184121 abstract "Objective: to observe the effect of Yiqi Huatan Quyu Fang(YHQF) on the 6-Keto-PGF1α and TXB2 in rats with coronary heart disease so to explore its therapeutic mechanism.Methods: rat models with coronary heart disease,made with high fat diet and intraperitoneal injection of pituitrin,were divided into normal group,model group,compound Danshen dripping pill(DSDP) group,YHQ high and low dose groups.6 weeks after the corresponding drug intervention,6-Keto-PGF1α and TXB2 contents were detected.Results: 6-Keto-PGF1α decreased significantly(P0.01) and TXB2 increased(P0.01);compared to model group,6-Keto-PGF1α increased significantly(P0.05 or P0.01) and TXB2 decreased(P0.01);both dose groups were superior to control group(P0.05 or P0.01).Conclusion: YHQF can treat coronary heart disease by increasing 6-Keto-PGF1α,decreasing TXB2 content and regulating the balance between 6-Keto-PGF1α,and TXB2 to restore the normal structure and function of vascular endothelial." @default.
- W2382184121 created "2016-06-24" @default.
- W2382184121 creator A5041740982 @default.
- W2382184121 date "2011-01-01" @default.
- W2382184121 modified "2023-09-28" @default.
- W2382184121 title "Effect of Yiqi Huatan Quyu Fang on 6-Keto-PGF_(1α) and TXB_2 in Rats with Coronary Heart Disease" @default.
- W2382184121 hasPublicationYear "2011" @default.
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