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- W2382280742 abstract "Objective To detect the quantity and ability of CD4+T and CD8+ T cells in peripheral blood and liver tissues distribution and quantity of dendritic cells(DC) and subgroup lymphocytes in CHB site and prognosis of patients with chronic Hepatitis B.Methods(1)The quantity of CD4+T and CD8+ T cells in peripheral blood was detected by flow cytometry(FCM) in 36 patients with hepatitis B and 20 cases of controls;(2)Immunohistochemisty was done on 64 specimens of patients with chronic Hepatitis B to count the S-100 protein positive DC and CD4+T,CD8+T in ten high power fields within a specimen.and to observe the relationship of prognosis of patients and the types,the quantity and the distributing of immunocytes.Results it is familiar that CD4+T exist in the portal areas,but the CD4+T is not as mush as CD8+T.And the shape of the DCs is irregular.Almost all of the DCs distribute in areas of necrosis and Interstitial areas associated with lymphocytes,usually not in liver cells.The number of DC is more in the cases of those that have more necrotic areas and lymphocytes infiltration.The progress and the number of CD4+T and CD8+T have positive relationship(r=0.95,r=0.94).Conclusion it is helpful in the process of analyzing,deciding and treating if we should consider the type,Lymphocyte subpopulation,the function and relationship of the immunologic cells and more as evaluating the immune-micro-environment of chronic hepatitis." @default.
- W2382280742 created "2016-06-24" @default.
- W2382280742 creator A5054536576 @default.
- W2382280742 date "2008-01-01" @default.
- W2382280742 modified "2023-09-26" @default.
- W2382280742 title "Relations between Liver Tissue Immunity and Peripheral Blood Immunity of Patients with Chronic Hepatitis B" @default.
- W2382280742 hasPublicationYear "2008" @default.
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