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- W2382296986 abstract "Objective To observe the level of CD4+CD25+regulatory T cells(Treg)and cytokines IL-10 and TGF-β in peripheral blood in infants with bronchiolitis caused by respiratory virus(RSV),and discuss the relationship between Treg and RSV bronchiolitis.Methods The percentage of Treg in peripheral blood in 31 infants with RSV bronchiolitis,27 infants with non-RSV pneumonia and 24 healthy infants were detected by flow cytometry.The level of their cytokins IL-10 and TGF-β in peripheral blood was measured by ELISA.Results The percentage of Treg in peripheral blood in infants with RSV bronchiolitis(10.71±1.11)% was significantly lower than these in infants with non-RSV pneumonia(12.73±1.35)% and healthy infants(13.24±1.13)%(P0.01).The level of IL-10 and TGF-β in peripheral blood in infants with RSV bronchiolitis(89.83±9.43,1 019.17±353.32)ng/L were significantly lower than these in infants with non-RSV pneumonia(116.40±14.10,1 979.50±462.30)ng/L and healthy infants(124.22±18.38,2 139.88±484.75)ng/L(P0.01).Conclusion There are a decrease of the percentage of Treg and their insufficient function in peripheral blood in infants with RSV bronchiolitis,Treg may be an important factor of the pathogenesis of RSV bronchiolitis." @default.
- W2382296986 created "2016-06-24" @default.
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- W2382296986 date "2011-01-01" @default.
- W2382296986 modified "2023-10-06" @default.
- W2382296986 title "The Detection and significance of CD4~+CD25~+ regulatory T cells,IL-10 and TGF-β in peripheral blood in infants with bronchiolitis caused by respiratory syncytial virus" @default.
- W2382296986 hasPublicationYear "2011" @default.
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