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- W2382302267 abstract "Objective To explore the clinical efficacy on renal anemia with different modes of operation in treatment of secondary hyperparathyroidism( SHPT) caused by uremia. Methods A retrospective analysis had been carried out in 30 patients with uremia caused SHPT. According to different surgical methods,these patients were randomly divided into A,B and C groups,patients in group A were treated by PTX plus autologous forearm brachioradialis muscle planting transplant,patients in group B were treated by PTX plus autologous forearm subcutaneous injection transplantation and patients in group C were treated by TPTX,10 cases in each group. Hemoglobin( Hb) and hematokrit( Hct) were observed in patients with iPTH before operation and in third,sixth and twelfth months after operation. At the same time,the dosage of erythropoietin had been recorded. Results The level of serum iPTH was higher in patients of these 3 groups,but there was no statistically significant difference among these groups. Since three months after operation,the data of patients in three groups regarding levels of iPTH were significantly decreased( P 0. 01),and remained in the ideal level after six months. Since three months,the difference according to iPTH level of group C compared with that of group A and group B was significant( P 0. 01). The data of Hb and Hct had been gradually increased in patients of 3 groups after operation till 12 months,it had statistical difference compared with those of pre- operation( P 0. 01 and 0. 05). The anemia in group C compared with groups A and B had significantly been improved( P 0. 05). The dosage of erythropoietin before surgery in these 3 groups had no statistical difference,the dosage of erythropoietin had gradually been reduced after operation till to 6 months,and the difference in dosage of erythropoietin was statistically significant( P 0. 01). Conclusion Three kinds of surgery including PTX with autologous forearm brachioradialis muscle planting transplantation,PTX with autologous forearm subcutaneously injection transplantation and TPTX can quickly lower the level of iPTH and significantly improve renal anemia,and reduce the dosage of erythropoietin. The method of TPTX in correcting renal anemia and reducing the dosage of erythropoietin is better than other two kinds of operation modes." @default.
- W2382302267 created "2016-06-24" @default.
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- W2382302267 date "2014-01-01" @default.
- W2382302267 modified "2023-09-23" @default.
- W2382302267 title "Observation on different surgical methods for secondary hyperparathyroidism on renal anemia" @default.
- W2382302267 hasPublicationYear "2014" @default.
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