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- W2382307430 abstract "Objective To observe the effects of matrine on weight,serum lipids and anti-oxidative capacity in high-fatted SD rats.Methods Fouty-four SD rats were randomly divided into five groups:control group,high-lipid group,high-dose matrine group(30 mg·kg-1·d-1),middle-dose matrine group(15 mg·kg-1·d-1) and low-dose matrine group(7.5 mg·kg-1·d-1).SD rats were fed with ordinary diet and administered physiological saline in control group and high-lipid group and other SD rats were administered matrine and fed with high-fat diet.Food intake was monitored daily,and body weight was weighed weekly at set time.At the end of the eighth week,blood glucose and serum biochemical indexes were determined.Results Matrine significantly reduced the body weight(P0.05).Middle-dose matrine decreased blood glucose,the fasting serum levels of malondialdehyde,free fatty acids,glutamic-pyruvic transaminase and elevated the total antioxidative capacity.Conclusion Matrine can significantly inhibit the weight gain of high-fatted rats,regulate the blood lipids and blood glucose metabolism disorders,enhance anti-lipid peroxidation and protect the liver function." @default.
- W2382307430 created "2016-06-24" @default.
- W2382307430 creator A5063880073 @default.
- W2382307430 date "2008-01-01" @default.
- W2382307430 modified "2023-09-27" @default.
- W2382307430 title "Effects of Matrine on Weight,Serum Lipids and Anti-oxidative Capacity in High-fatted Rats" @default.
- W2382307430 hasPublicationYear "2008" @default.
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