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- W2382307555 abstract "Objective: To investigate the expression of cardiac angiotensinⅡ(AngⅡ), the jeopardy score of coronary artery lesion by angiography, and their correlations in patients with stable angina (SA) or unstable angina (UA). Method: The 20 patients with UA, 17 patients with SA and 18 patients excluding coronary heart disease (control) were studied. Blood samples were collected during percutaneous coronary intervention (PCI). The aorta-coronary sinus gradient of was measured as cardiac AngⅡconcentration. The AngⅡ concentration of peripheral blood was also measured. The jeopardy score for coronary artery lesion was evaluated according to the method by Califf. Result: Either cardiac or peripheral AngⅡconcentration in angina patients, especially in UA patients was higher than that in control group (P 0.01), but the jeopardy score showed no difference between UA and SA. The cardiac AngⅡ showed a closely positive correlation with jeopardy score (P 0.01).The peripheral AngⅡshowed a positive correlation with jeopardy score (P 0.05) in UA, while no obvious correlation was observed in SA. Conclusion: The cardiac AngⅡmay play as a aggravating factor in the pathophysiological progress of atherosclerosis and coronary heart disease. Coronary angiography combined with detection of cardiac AngⅡconcentration may better describe the lesion of coronary artery, and may better evaluate the prognosis of coronary heart disease patients." @default.
- W2382307555 created "2016-06-24" @default.
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- W2382307555 date "2004-01-01" @default.
- W2382307555 modified "2023-09-27" @default.
- W2382307555 title "Cardiac angiotensin IIand jeopardy score of coronary artery lesion by angiography in angina patients" @default.
- W2382307555 hasPublicationYear "2004" @default.
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