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- W2382365911 abstract "Objective To research the mechanism of Huazhuo Jiedu Tiaogan prescription on anti-hepatic fibrosis.Methods 120 health male SD rats were randomly divided into six groups:control group,model group,colchicines prevention group,Huazhuo Jiedu Tiaogan prescription prevention group,colchicines treatment group and Huazhuo Jiedu Tiaogan prescription treatment group,20 rats in each group.The model rats with hepatic fibrosis were induced intraperitoneal injection of un-inactivated porcine serum.Colchicines and Huazhuo Jiedu Tiaogan prescription were adopted to treat.The expression of tissue inhibitor of metalloproteinases(TIMPs)was measured with immunohistochemistry at the No.8 week and No.12 week of establishing model,executing 10 rats.Results Huazhuo Jiedu Tiaogan prescription inhibited obviously the expression of TIMP-1 in hepatic tissue of rat with hepatic fibrosis in comparison with that in colchicines.Conclusion Huazhuo Jiedu Tiaogan prescription can prevent and treat hepatic fibrosis rat,its mechanism maybe inhibit the expression of TIMP-1 in hepatic tissue." @default.
- W2382365911 created "2016-06-24" @default.
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- W2382365911 date "2010-01-01" @default.
- W2382365911 modified "2023-09-24" @default.
- W2382365911 title "Effect of Huazhuo Jiedu Tiaogan prescription on expression of TIMP-1 in hepatic tissue of rat with hepatic fibrosis" @default.
- W2382365911 hasPublicationYear "2010" @default.
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