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- W2382398740 abstract "Objective To research the Extraction and purification process of total flavonoids in Centipeda minima(L.)A.Br.et Aschers,and investigate its antitumor activity. Methods Optimize the ethanol extraction process, while using macroporous resin, organic solvent extraction and polyamide chromatography method extracts of total flavonoids was refined. Finally using intragastric administration method to research the antitumor effect of total flavonoids. Results According orthogonal experiment to determine the optimal extraction conditions of total flavonoids was 70% of ethanol,2 times, each time 2 h, 8 times the amount of solvent. Up 762% content after Refined total flavonoids. In addition, Centipeda minima(L.)A.Br.et Aschers. flavonoids on S180 solid tumor inhibition rate was 7192%. Conclusion The extraction and purification process is simple, safe and feasible. Centipeda minima(L.)A.Br.et Aschers. flavonoids on S180 solid tumors significantly inhibited." @default.
- W2382398740 created "2016-06-24" @default.
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- W2382398740 date "2010-01-01" @default.
- W2382398740 modified "2023-09-26" @default.
- W2382398740 title "The Extraction of total flavonoids in Centipeda minima(L.)A.Br.et Aschers. and inhibitory effect on S180 Solid Tumor Study" @default.
- W2382398740 hasPublicationYear "2010" @default.
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