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- W2382413047 abstract "Objective Origin recognition complex1(ORC1) had been corcerned with the vascular muscle cell(VSMC) of proliferation.To explore ORC1 effection in proliferation index of VSMC.Methods VSMC of rat thoracic aorta was obtained by the adherence method of tissue culture.The different stages of VSMC proliferation were determined by flow cytometry;The protein expression of ORC1 was observed by immunocytochemistry.Results Cultured VSMC was confirmed by light microscope and immunocytochemistry.the ration of proliferation during the quiescence stage of VSMC was(10.40±3.52)%,The protein expression of ORC1 was low or not found;After VSMC was stimulated with serum,the ration of proliferation during the proliferation stage of VSMC was(33.91±13.42)%,protein expression of ORC1 increased significantly at 24 hour(P0.01).Conclusion ORC1 may have concerned with the the proliferation of different process of VSMC." @default.
- W2382413047 created "2016-06-24" @default.
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- W2382413047 date "2011-01-01" @default.
- W2382413047 modified "2023-09-28" @default.
- W2382413047 title "Effection of ORC1 during the proliferation of vascular smooth muscle cells" @default.
- W2382413047 hasPublicationYear "2011" @default.
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