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- W2382448078 abstract "Objective To assess the value of the AFP(the alpha fetoprotein)level for the prognosis of acute liver failure disease.Methods 71 patients with acute liver failure were investigated from 302 Military Hospital during Jan 2009 to Jan 2012.AFP level in serum was detected.All the patients were followed for 3 months.The patients were divided into survivor group(n=21)and non-survivor group(n=50)according to the outcome.AFP level was compared between survivor group and non-survivor using independent variable non-parameter test and the role of AFP level in the prognosis of the ALF patients were analyzed by the receiver operating characteristic curve(ROC curve)and the fourfold table.Results AFP level in survivor group(186 μg/L)was much higher than non-survivor(36.5 μg/L,P=0.004).The cutoff value of the AFP level evaluated by ROC curve was 121 μg/L.The area under curve(AUC)was 0.719 with the sensibility 0.714 and specificity 0.700,and the accuracy for prognosis was 0.714 with the negative predictive value 85.4%,the positive predictive value 50%.Conclusions The cutoff value of the AFP level for the prognosis of acute liver failure disease was 121 μg/L,with a better sensibility,specificity,diagnosis accuracy,and a higher negative predictive value." @default.
- W2382448078 created "2016-06-24" @default.
- W2382448078 creator A5033399642 @default.
- W2382448078 date "2013-01-01" @default.
- W2382448078 modified "2023-09-28" @default.
- W2382448078 title "Assess the value of the AFP level for the prognosis of acute liver failure disease with ROC curve" @default.
- W2382448078 hasPublicationYear "2013" @default.
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