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- W2382459088 abstract "Objective To study the genotypes distribution of human papillomavirus(HPV) in cervical cell samples of women in Beijing city and to provide epidemiological data for the prevention of cervical cancer and the development of vaccine.Methods Polymerase chain reaction(PCR) and gene-chips technique were used to detect 23 types of HPV DNA in cervical cell samples from 2050 cases of women in Beijing area and the infection states among all subtypes were analyzed. Results The total infection rate of HPV was 25.85%(530/2050). The positive rate of high-risk type was 17.37%(356/2050) and lowrisk type was 5.02%(103/2050). In 23 subtypes, the most common types were 16, 6, 58, 52, 43; 44, 39 and MM4 were not detected. HPV single infection was detected in 20 kinds of type and the positive rate was 19.12%(392/2050) and the main subtype was HPV16, accounted for 21.43%(84/392). Mixed infection rate of HPV was 6.73(138/2050); double infection was the most common, accounting for 78.79%(109/138), where HPV11+43, HPV16+6 were the main types of mixed infection.Conclusion The most common types of high-risk HPV in female cervical cells are HPV16, HPV52, HPV58 and low-risk types are HPV6, HPV43. Investigation of HPV genotypes in cervical cells can effectively reduce the probability of catching cervical cancer, and provide epidemiological data for research and development of cervical cancer vaccine." @default.
- W2382459088 created "2016-06-24" @default.
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- W2382459088 date "2013-01-01" @default.
- W2382459088 modified "2023-09-23" @default.
- W2382459088 title "Study on human papillomavirus genotypes among cervical cells of female patients" @default.
- W2382459088 hasPublicationYear "2013" @default.
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