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- W2382496479 abstract "Objective To assess the association of plasma interleukin-33(IL-33)level with the prognosis in the patients with acute coronary syndrome(ACS).Methods The plasma concentration of IL-33 in 60 cases of the patients with ACS(including 20 cases with unstable angina pectoris,20 cases with non-ST-segment elevation myocardial infarction and 20 cases with ST-segment elevation myocardial infarction)at the day of admission and 20 cases of non-coronary heart disease patients(control group)were measured using enzyme-linked immunosorbent assay.The plasma concentration of IL-33 in 13 cases of post-directing PCI-patients with STEMI was also obtained using the same method after three months of intencified medical therapy.Results The plasma concentration of IL-33 in subgroups of ACS patients was significantly lower than that in control group,(42.56±10.17)ng/L,(40.65±12.99)ng/L,(30.46±4.97)ng/L vs(56.66±5.09)ng/L(all P0.01).Logistic analysis indicated that the lower level of IL-33 was an independent risk factor for ACS(OR=0.245,95%CI 0.158-0.442,P=0.002).The concentrations of IL-33 correlated inversely with fasting blood glucose and triglyceride.IL-33 level of 13 STEMI patients increased dramaticly after percutaneous coronary intervention and three months of medical therapy(46.47±12.33)ng/L vs(29.45±3.01)ng/L(P=0.001).Conclusion The decreased plasma IL-33 concentration might be an independent risk factor for the vulnerable plaques and the severity of coronary lesions,and could be used as one of the independent predictors for the prognosis in patients with ACS." @default.
- W2382496479 created "2016-06-24" @default.
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- W2382496479 date "2009-01-01" @default.
- W2382496479 modified "2023-09-24" @default.
- W2382496479 title "Relationships between level of plasma interleukin-33 and prognosis in patients with acute coronary syndrome" @default.
- W2382496479 hasPublicationYear "2009" @default.
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