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- W2382503504 abstract "Objective In recent years,as the incidence of diabetes is increasing day by day,anti-diabetic drugs have been paid more and more attention.This paper mainly introduced the domestic and international medicine for treating diabetes and the research direction of antidiabetic drugs.In order to provide references for clinical rational drug use.Methods Refer to the literatures,and summarize the summary.Results According to the mechanism and structure,the diabetes treating medicine are insulin secretagogues,insulin sensitizers,alpha glucosidase inhibitor,insulin and insulin analogues,two peptide peptidaseiv(DPP IV) inhibitors,other oral antidiabetic drugs.Metformin and acarbose gliclazide are used widely in the clinical.Co-administration of antidiabetic drugs were often used in the treatment of diabetes.Conclusion The occurrence and development of diabetes had a closely relationship with the disorder function of enzymes including alpha glucosidase,aldose reductase,nitric oxide synthase,angiotensin converting enzyme,carnitine palmitoyltransferase I and II,protein kinase C,two peptide peptidase IV,protein tyrosine kinases,protein tyrosine phosphatase.These enzymes maybe the new targets of diabetes treatment and maybe the new trendency of diabetes drug development." @default.
- W2382503504 created "2016-06-24" @default.
- W2382503504 creator A5062308904 @default.
- W2382503504 date "2012-01-01" @default.
- W2382503504 modified "2023-09-23" @default.
- W2382503504 title "Drug Treatment for Diabetes Mellitus" @default.
- W2382503504 hasPublicationYear "2012" @default.
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