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- W2382526420 abstract "Objective The purpose is to evaluate the relationship between the genetic polymorphism of TNFA gene and the marginal bone loss around the implants before stage Ⅱ and to find the related factors influencing the marginal bone loss thus to predict the long stability of implants. Methods A case-control study was used. Patients demonstrating marginal bone loss around implants at stage-Ⅱ surgery were designated as the 'marginal bone loss (+)' group and those without bone loss as the 'marginal bone loss (-)' group. Genomic DNA from buccal mucosa was amplified by the polymerase chain reaction (PCR) to detect TNFA Gene. Results There were significant differences in the distributions of smoking between the two groups. However,the distribution of the TNFA-308 genotype was not significant in both groups. Multiple logistic regression shows the patients smoking had a 8.403 times greater likelihood of marginal bone loss than those without smoking. The differences between the other risk factors were non-significant. Conclusion Smoking is associated with early marginal bone loss and the TNFA-308 genotype in individual is not the risking factor of early marginal bone loss." @default.
- W2382526420 created "2016-06-24" @default.
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- W2382526420 date "2009-01-01" @default.
- W2382526420 modified "2023-09-26" @default.
- W2382526420 title "The Relationship between TNFA-308 Gene Polymorphism and Marginal Bone Loss Around Dental Implants" @default.
- W2382526420 hasPublicationYear "2009" @default.
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