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- W2382550126 abstract "Objective To discuss the laboratory indicators of amikacin on the early damage of renal function.Methods We tested the laboratory urea nitrogen(BUN),creatinine(Scr),cysteine protease inhibitor C(Cys-C),N-acetyl-β-D-glucosaminidase(NAG),microalbuminuria(MAU),β2-microglobulin(β2-M)from 145 cases of negative qua-litative urinary protein patients with bacterial infection before and after amikacin treatment,with 100 healthy people as control group.Results After the application of amikacin,urinary Cys-C,NAG,MAU were significantly higher than those before the application,and the differences were significant(P0.01).The levels of BUN,Scr,β2-M between the application before and after amikacin were not significant difference(P0.05).Conclusion Negative qualitative urine protein,normal content of BUN,Scr can not exclude the early damage of amikacin on the renal function,and urinary Cys-C,NAG,MAU are laboratory diagnosis sensitive and reliable indicators of early renal function.Urine β2-M may not suitable for monitoring the early damage of renal function of patients with bacterial infections after amikacin treatment." @default.
- W2382550126 created "2016-06-24" @default.
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- W2382550126 date "2011-01-01" @default.
- W2382550126 modified "2023-09-24" @default.
- W2382550126 title "Study on laboratory indicators of amikacin on the early damage of renal function" @default.
- W2382550126 hasPublicationYear "2011" @default.
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