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- W2382567925 abstract "Objective To study the expressions of substance P(SP) in trigeminal ganglia in rats with unilateral chew,and to discuss the mechanism of temporomandibular disorders. Methods 30 Wistar male rats were randomly divided into 6 groups,including 3 experimental groups and 3 control groups,5 rats in each group. The molar of right maxillas and mandibulae in experimental groups were ground to the gingival level without occlusal contact. The section of trigeminal ganglia underwent the immunohistological study to evaluate the expressions of SP by SABC method. Light microscopic photo analytic software and SPSS10. 0 statistical software were used. Results The percentage of SP positive neurons in TG in 3 experimental groups were significantly decreased compared with control group (P0.01,P0.05) ,The decreased extent in nonchewing side was much higher than that in the chewing side(P0.01,P0.05). Conclusion The SP might participate in the histopathologic mechanism of temporomandibular disorders. The releas amount of SP in TG is different between chewing and nonchewing side under the condition of unilateral mastication." @default.
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- W2382567925 date "2007-01-01" @default.
- W2382567925 modified "2023-09-25" @default.
- W2382567925 title "Expressions of substance P in trigeminal ganglia in unilateral chew rats" @default.
- W2382567925 hasPublicationYear "2007" @default.
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