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- W2382644080 abstract "Objective To observe the short-term efficacy of the domestic anti-malaria drugs pyronaridine phosphate and pyronaridine phosphate combined with dihydroartemisinin for treatment of malaria in the state of Eritrea. Methods People with plasmodium were selected as the subjects and were followed up daily by blood examination after they took the drugs. Results The mean asexual clearance time of Plasmodium vivax and P. falciparum was 32.00 h and 50.18 h after the single-drug therapy respectively and 24.00 h, and 27.69 h after the combined-drug therapy respectively. As to the chloroquine resistant falciparum malaria cases, the mean asexual clearance time of the combined-drug therapy was 24 h. The fever of all 36 cases stopped before the finish of the treatment. The adverse reaction was mild and transient. On the 7th day after the 1st dose in the single-drug therapy, gametocytes were found in the blood of 55.56% falciperum malaria cases, higher than the 18.18% in the combined-drug therapy. Conclusion Both therapeutic methods showed the 100% cure rate in Eritrea although the combined-drug therapy seemed more effective than the single-drug therapy." @default.
- W2382644080 created "2016-06-24" @default.
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- W2382644080 date "2001-01-01" @default.
- W2382644080 modified "2023-09-28" @default.
- W2382644080 title "OBSERVATION ON EFFICACY OF PYRONARIDINE PHOSPHATE AND IT COMBINED WITH DIHYDROARTEMISININ FOR TREATMENT OF MALARIA IN ERITREA, AFRICA" @default.
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