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- W2382654865 abstract "Objective This study was to research into a new adoptive immunotherapy against hepatic cancer. Methods Syngeneic BALB/c mice were subcutaneously injected with cells of H22 cell line, which was hepatic cancer cells of murine origin, and a tumor bearing mice model was established. Then the combinative therapy with activated killer cells (AK), IL 2, and an anti IL 2 receptor α chain monoclonal antibody (aIL 2RαMAb) was performed in order to explore its anti tumor role. Results LAK and CTL activities, the lymphocyte transformation rate in the group of combined therapy were all significantly higher than those of controls (P0 01), but NK activity remained unchanged. Tumor bearing mice in the group of combined therapy showed apparent growth inhibition of subcutaneous tumor and significant prolongation of survival time. Conclusion When IL 2, aIL 2RαMAb and AK cells are used combinatively, the anti tumor effect is evidently intensified." @default.
- W2382654865 created "2016-06-24" @default.
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- W2382654865 date "2000-01-01" @default.
- W2382654865 modified "2023-09-28" @default.
- W2382654865 title "Experimental study on the treatment of hepatic carcinoma by anti-interleukin-2 receptor α chain monoclo nal antibody and activated killer cells" @default.
- W2382654865 hasPublicationYear "2000" @default.
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