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- W2382672084 abstract "Objective:To observe influence of rosuvastatin and atorvastatin on C-reactive protein,granule membrane protein-140 and endothelial function of patients with unstable angina.Methods:Selected 66 cases patients with unstable angina and randomly divided into treatment group 1 and treatment group 2 with 33 cases in each group,then selected other 25 healthy volunteers as control group.Investigated and compared participants' general information including age,gender,and CRP,GMP140,brachial artery diastolic dysfunction(FDM)before and after treatment.Results:The levels of TC,LDL-C in treatment group 1 and group 2 were significantly decreased while HDL-C increased(P0.05).TC and LDL-C of treatment group 1 was significantly lower than that in group 2(P0.05).Before treatment,levels of CRP,GMP140 in treatment group 1 and group 2 were significantly higher than that in control group,the FDM was significantly lower than the control group,the difference was statistically significant(P0.05);after treatment,the levels of CRP,GMP140 in treatment group 1 and group 2 decreased but level of FDM increased(P0.05).the levels of GMP140 in treatment group 1 were significant lower than that in treatment group 2(P0.05).Conclusion:Both rosuvastatin and atorvastatin can decrease the inflammatory response and platelet accumulation in patients with unstable angina,they both can improve the blood lipid status and endothelial function,and rosuvastatin shows better efficiency in improving status of platelet accumulation of rosuvastatin." @default.
- W2382672084 created "2016-06-24" @default.
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- W2382672084 date "2014-01-01" @default.
- W2382672084 modified "2023-09-26" @default.
- W2382672084 title "Efficiency comparison of rosuvastatin and atorvastatin on C-reactive protein,granule membrane protein-140 and endothelial function of patients with unstable angina" @default.
- W2382672084 hasPublicationYear "2014" @default.
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